A3O™ Elemental Serum – Elm Biosciences

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01/09

436 Reviews

A3O™ Elemental Serum

Regular Price:$135.00Sale Price:$108.00

Smooths

Plumps

Brightens

Protects

A first-of-its-kind, patent-pending antioxidant serum powered by the A3O™ Complex, a triple-pathway anti-senescent molecule engineered to target visible signs of aging, including UV damage, pigmentation, dehydration, and irritation, while remaining gentle enough for sensitive skin.

The serum delivers transformative results through a single, intelligently developed formula.

40ml / 1.35 fl oz

Subscription purchase typeMONTHLY DELIVERYSave $27.00Regular price: $135.00 $108.00

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One time only purchase typeONE-TIME PURCHASE$135.00

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For best results, pair with:

A3O™ Elemental Night CreamGET BOTH & SAVE –$216 $300

The serum delivers transformative results through a single, intelligently developed formula.

40ml / 1.35 fl oz

100% reported improved skin texture

100% achieved intense hydration

97% reported stronger skin resilience

Ingredients

More than just a protective shield, A3O™ actively supports the skin’s natural collagen production, improves texture, and helps support the skin's natural moisture barrier, making it the cornerstone of healthy aging.  Coupled with:

FULL INGREDIENT LIST WATER (EAU), GLYCERIN, PROPANEDIOL, BUTYROSPERMUM PARKII (SHEA) BUTTER, CAPRYLIC/CAPRIC TRIGLYCERIDE, ETHYL LINOLEATE, ACETYL ZINGERONE, ETHYLHEXYL OLIVATE, LYSOLECITHIN, SCLEROTIUM GUM, PARFUM, CAPRYLYL GLYCOL, PENTYLENE GLYCOL, TOCOPHERYL ACETATE, BAKUCHIOL, PULLULAN, XANTHAN GUM, ETHYL OLEATE, SYNTHETIC FLUORPHLOGOPITE, ETHYL PALMITATE, PHENETHYL ALCOHOL, CAPRYLHYDROXAMIC ACID, SILICA, SQUALANE, ETHYL LINOLENATE, BENZYL ALCOHOL, SODIUM HYALURONATE, TIN OXIDE, PHENOXYETHANOL, CITRIC ACID, TANACETUM ANNUUM FLOWER OIL, LIMONENE, LINALOOL, PINENE, LINALYL ACETATE, ALPHA-ISOMETHYL IONONE, BETA-CARYOPHYLLENE, ALGIN, ETHYLHEXYLGLYCERIN, TITANIUM DIOXIDE (CI 77891), IRON OXIDES (CI 77492, CI 77491).

Recommended usage

Apply 1-2 pumps to clean, dry skin morning and night. Gently press into face, neck, and décolleté. Follow with moisturizer or SPF as needed.

Benefits

how to use

A single, intelligently-designed serum.

  1. Apply 1–2 pumps to clean, dry skin morning and night. A3O™ is designed to layer well under other treatments and makeup.

  2. Gently press into face, neck and decollete.

  3. Follow with moisturizer or SPF as needed.

  4. Complement the A3O™ Elemental Serum with the [Inner Dose™ Daily Skin Supplement](/content/products/inner-dose-daily-skin-supplement "Inner Dose™ Daily Skin Supplement"/index.html) for full inside-out results.

A3O™ ELEMENTAL SERUM

first-of-its-kind antioxidant serum

Silky, glowy serum

Velvety, cooling, weightless hydration

Intoxicating, barely-there scent

Clinically tested on sensitive, mature, and acne-prone skin

Skin looks soft, smooth, and makeup-ready — no stickiness or residue

Cruelty-Free. Vegan. 
Non-Comedogenic. Gluten-Free.
 Dermatologist-Tested & Developed.

Advanced Ingredients, Intelligently Sourced

Our ingredients are meticulously selected to create formulas that bring breakthrough science into effective daily skincare.

Full List

Our proprietary complex that protects and supports

01

A3O™ Complex

Hydrates and plumps

02

Hyaluronic Acid

Reduces redness

03

Blue Tansy

Softens and protects

04

Squalane

Calms and soothes

05

Vitamin E

01/05

Full List

a3o™ elemental serum

First-of-its-kind, patent-pending antioxidant serum powered by the A3O™ Complex to actively support the skin’s natural collagen production, improve texture, enhance tone and strengthen its overall barrier function.

A3O™ COMPLEX

Combining Acetyl Zingerone, Bakuchiol, and a fatty acid ester, our ​​Patent-pending, triple-pathway anti-senescent molecule helps firm skin, enhances tone, and brightens the complexion with results that rival Vitamin C, without the irritation.*

Developed over years of R&D, including clinical work and published research on individual components by our dermatologist-led medical advisory board, we were very intentional about each ingredient and the optimal method to combine them in our complex. We believe this will reset the industry’s expectations for antioxidant molecules moving forward.

Calm instead of irritate. Stable in sunlight instead of breaking down. Stimulating the skin’s natural Collagen and helping set the stage for aging well*.

HYALURONIC ACID

​​​​Deeply hydrates and plumps for smoother, more elastic-feeling skin*.​​​​

SQUALANE

​​​​Helps to strengthen the skin’s natural moisture barrier to lock in hydration*.​​

VITAMIN E

​​​​Provides antioxidant protection and helps retain skin moisture*.​​

BLUE TANSY

​​​​Soothes dry, irritated skin and is gentle for sensitive skin*.​​

REFERENCES

1. Chaudhuri, R.K., Meyer, T., Premi, S. and Brash, D. (2020), Acetyl zingerone: An efficacious multifunctional ingredient for continued protection against ongoing DNA damage in melanocytes after sun exposure ends. Int J Cosmet Sci, 42: 36-45. https://doi.org/10.1111/ics.12582

2. Dhaliwal S, Rybak I, Pourang A, et al. Randomized double-blind vehicle controlled study of the effects of topical acetyl zingerone on photoaging. J Cosmet Dermatol. 2021; 20: 166–173. https://doi.org/10.1111/jocd.13464

3. Meyer, T.A.; Swindell, W.R.; Chaudhuri, R.K. Acetyl Zingerone: A Photostable Multifunctional Skincare Ingredient That Combats Features of Intrinsic and Extrinsic Skin Aging. Antioxidants 2023, 12, 1168. https://doi.org/10.3390/antiox12061168

4. Srivastava, J.; Young, M.M.; Yadav, V.K.; Phadatare, P.R.; Meyer, T.A.; Chaudhuri, R.K.; Premi, S. The Role of Acetyl Zingerone and Its Derivatives in Inhibiting UV-Induced, Incident, and Delayed Cyclobutane Pyrimidine Dimers. Antioxidants 2023, 12, 278. https://doi.org/10.3390/antiox12020278

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

MEET THE ELEMENTAL SERUM

Powered by our patent-pending A30™ complex

A3O™ is a next-generation antioxidant engineered to target the visible signs of cellular aging — without the irritation or instability of Vitamin C.

Meet A3O™

Customer reviews

4.53

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All18-2425-3435-4445-5455-6465-7475+

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AllImproved HydrationSmoothed Crow's FeetSoftened Fine LinesImproved Skin TextureBrightened Complexion

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AllAging skinAcne / breakoutsRednessDullnessDrynessFine lines / wrinkles

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AllDryOilyCombinationAgingSensitiveDull

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LT

Lindsay T

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8 hours ago

This serum is amazing! My skin glows for aong long after I use this. This has brought so much life back to my skin.

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TW

Teresa W

Verified buyer

Age:65-74

Benefits:Improved Hydration, Improved Skin Texture

Skin concerns:Aging skin

Skin type:Aging

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yesterday

Love it!

Love it!

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JN

Jacqueline N

Verified buyer

Age:55-64

Benefits:Softened Fine Lines, Brightened Complexion, Improved Skin Texture, Smoothed Crow's Feet

Skin concerns:Redness, Aging skin, Fine lines / wrinkles

Skin type:Combination, Sensitive, Aging

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yesterday

Amazing

In my younger years I was skincare certified I have tried all the best of the best this product by far is the most effective within 2 days I saw a difference in skin under my eyes all over. The scent is delicious the texture is simply perfect I subscribed to it after a weeks use. Thank you Martha for creating such an amazing product !

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PP

Patricia P

Verified buyer

Age:75+

Benefits:Improved Skin Texture

Skin concerns:Dryness, Aging skin

Skin type:Sensitive

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4 days ago

Natural feeling soothing moisturizer.

I have very sensitive skin and this product feels good, absorbs beautifully on my skin and has an earthy texture. I highly recommend using this wonderful serum.

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MK

Melissa K

Verified buyer

Age:55-64

Benefits:Brightened Complexion

Skin concerns:Aging skin, Fine lines / wrinkles, Acne / breakouts

Skin type:Combination

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4 days ago

Love it

So far I am really living this serum.

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Reviewed on See Elm Biosciences on Junip (opens in a new tab)

FAQ

WE’VE DONE OUR RESEARCH

WHEN CAN I EXPECT TO SEE RESULTS?

PlusMinus

Most users begin noticing visible improvements in clarity, texture, and tone within 2–4 weeks. Results continue to build with consistent use.

WHO ARE YOUR PRODUCTS FORMULATED FOR?

PlusMinus

Elm is designed for real skin — including sensitive, aging, hormonal, or inflammation-prone. Our formulas are clinically tested to work across a wide range of tones, textures, and needs.

WHAT PAIRS WELL WITH THE SERUM?

PlusMinus

For optimal results, pair with our A3O™ Elemental Night Cream and our Inner Dose™ Daily Skin Supplement.

The A3O™ Elemental Night Cream enhances texture, radiance, and firmness, while the Inner Dose™ Daily Skin Supplement targets aging from the inside out.

You can also layer with your favorite moisturizer or SPF.

how often should i use the serum?

PlusMinus

Apply morning and night to clean, dry skin. A3O™ is gentle enough for daily use — even for sensitive skin.

Will this work for sensitive skin?

PlusMinus

Yes. A3O™ was designed to be a smarter, more stable alternative to Vitamin C — with none of the irritation, stinging, or sensitivity many people experience with traditional actives. It’s tested safe for sensitive skin and post-procedure use.

View All FAQs

INTERNAL SUPPORT. EXTERNAL DEFENSE.

Our A3O™ Complete Skin Renewal bundle forms a streamlined, clinically-advanced system designed to restore skin clarity, strengthen the barrier, and build long-term resilience—from the inside out.

Start Your Protocol

Discover the A3O™ Complete Skin Renewal

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