A3O™ Complete Skin Renewal 2-Pack – Elm Biosciences

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01/07

4.7 (1019)

A3O™ Complete Skin Renewal 2-Pack

~~Regular Price:$700.00~~Sale Price:$504.00

Firms Skin

Hydrates

Supports Elasticity

The A3O™ Complete Skin Renewal Bundle delivers comprehensive, multi-layered support for healthier, more resilient skin.

The A3O™ Elemental Serum replenishes and strengthens the skin’s barrier, while A3O™ Night Cream enhances texture, radiance, and firmness. Complemented by the Inner Dose™ Daily Skin Supplement, which addresses internal triggers of aging such as inflammation, oxidative stress, and hormonal imbalance, this trio works synergistically to strengthen your skin’s foundation and address aging from every angle, for smoother, firmer, and more radiant skin overall.

2x A3O™ Elemental Night Cream: e50 mL / 1.69 fl oz

2x A3O™ Elemental Serum: 40ml / 1.35 fl oz

2x Inner Dose™ Daily Skin Supplement: 60 capsules / 2-month supply

1 Month

2 Month

SubscriptionSAVE $196.00~~$700.00~~ $504.00

Delivery every 60 Days
One supplement jar to start; refills in pouches
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One-time purchase~~$700.00~~ $630.00

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A3O™ Complete Skin Renewal 2-Pack

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The A3O™ Complete Skin Renewal Bundle delivers comprehensive, multi-layered support for healthier, more resilient skin.

2x A3O™ Elemental Night Cream: e50 mL / 1.69 fl oz

2x A3O™ Elemental Serum: 40ml / 1.35 fl oz

2x Inner Dose™ Daily Skin Supplement: 60 capsules / 2-month supply

93% agree skin looks more even

97% agree skin looks healthy

95% agree skin feels more hydrated

Ingredients

A3O™ Elemental Serum

A3O™ Complex – protects and supports
Hyaluronic Acid – hydrates and plumps skin
Squalane – helps visibly fortify the skin's natural moisture barrier
Vitamin E – antioxidant protection and moisture retention
Blue Tansy – soothes and calms irritated skin

A3O™ Elemental Night Cream

Trifarotenyl Caprylate – Clinically advanced retinoid for surface renewal
A3O™ Complex – Smooths, firms, and brightens
Ectoin– Antioxidant support and hydration
Carnosine – Improves firmness, reduces dullness

Inner Dose™ Daily Skin Supplement

Polypodium Leucotomos – Antioxidant and UV protection
Turmeric – Supports inflammatory balance
Vitamin D3 – Supports skin barrier and overall vitality
Astaxanthin – Enhances elasticity and hydration
Holy Basil / Tulsi – Reduces stress-related aging

Recommended usage

Take the Inner Dose™ Daily Skin Supplement daily with food, preferably in the morning.
Apply A3O™ Elemental Serum to clean skin and in the evening, follow with A3O™ Elemental Night Cream as part of your routine.

For optimal results, use consistently and pair with daily sunscreen.

Benefits

A3O™ Elemental Night Cream

Smooths the appearance of fine lines and refines skin texture
Supports firm, resilient, and elastic skin
Provides overnight hydration and strengthens the skin barrier
Promotes brighter, more even-looking skin
Gentle formula designed for nightly use

A3O™ Elemental Serum

Soothes dryness and calms irritated skin
Supports natural collagen production
Reduces the appearance of fine lines and wrinkles
Strengthens and protects the skin’s outer barrier

Inner Dose™ Daily Skin Supplement

Promotes photoprotection and internal UV defense*
Reduces signs of inflammation and oxidative stress*
Helps fade discoloration and dark spots over time*
Diminishes the appearance of dark spots and uneven pigmentation*
Visibly reduces signs of aging, including fine lines and wrinkles*
Supports the skin’s natural defense and repair processes

Complete the routine

A3O™ Complete Skin Renewal

~~Regular price: $350.00~~Sale price: $315.00

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[View product - A3O™ Complete Skin Renewal - Default Title](/content/products/a3o-complete-skin-renewal?variant=46078711529625 "View product - A3O™ Complete Skin Renewal - Default Title"/index.html)

How to Use

A multi-layered anti-aging system

Take [Inner Dose™ Daily Skin Supplement](/content/products/inner-dose-daily-skin-supplement-starter-kit "Inner Dose™ Daily Skin Supplement Starter Kit"/index.html) capsules daily with food,  preferably in the morning.
Apply [A3O™ Elemental Serum](/content/products/a3o-elemental-serum "A3O™ Elemental Serum"/index.html) to clean skin to strengthen and replenish the barrier.
In the evening, layer [A3O™ Elemental Night Cream](/content/products/a3o-elemental-night-cream "A3O™ Elemental Night Cream"/index.html) over serum to enhance texture, radiance,  and firmness.
During the day, follow with a moisturizer and sunscreen.

meet a3o™

It's Time to Rethink Your Vitamin C

Our patent-pending anti-senescence A3O™ Complex delivers smoothing, brightening, and firming benefits rival those of Vitamin C, with superior tolerability and no irritation.

A3O™

VITAMIN C

Hydration

Firmness

Wrinkles

Elasticity

Redness

Safe for Daily Use

Advanced Ingredients, Intelligently Sourced

Our ingredients are meticulously selected to create formulas that bring breakthrough science into effective daily skincare.

Full List

Our proprietary complex that protects and supports

A3O™ Complex

Improves texture and clarity

TRIFAROTENYL CAPRYLATE

Supports skin barrier

Ectoin

Improves firmness

Carnosine

Hydrates and plumps

Hyaluronic Acid

Reduces redness

Blue Tansy

Softens and protects

Squalane

Calms and soothes

Vitamin E

Supports photoprotection

Polypodium Leucotomos

Calms and soothes

Organic Turmeric

Adds vitality

Vitamin D3

Maintains skin elasticity

Astaxanthin

Adapts and balances

Holy Basil / Tulsi

01/13

Full List

a3o™ elemental night cream

A transformative, next-generation retinoid with no prescription needed.

A3O™ COMPLEX

Combining Acetyl Zingerone, Bakuchiol, and a fatty acid ester, our Patent-pending, triple-pathway anti-senescent molecule helps firm skin, enhances tone, and brightens the complexion with results that rival Vitamin C, without the irritation.*

Developed over years of R&D, including clinical work and published research on individual components by our dermatologist-led medical advisory board, we were very intentional about each ingredient and the optimal method to combine them in our complex. We believe this will reset the industry’s expectations for antioxidant molecules moving forward.

Calm instead of irritate. Stable in sunlight instead of breaking down. Stimulating the skin’s natural Collagen and helping set the stage for aging well*.

TRIFAROTENYL CAPRYLATE

A selective, retinoid derivative that helps improve the appearance of skin texture while being suitable for sensitive skin*.

ECTOIN

An antioxidant that helps protect skin from environmental stressors while supporting the skin’s moisture barrier and soothes dry, irritated skin*.

CARNOSINE

A potent peptide that helps protect the skin from the visible signs of aging, supports firmer feeling skin, and brightens dull-looking skin*.

a3o™ elemental serum

First-of-its-kind, patent-pending antioxidant serum powered by the A3O™ Complex to actively support the skin’s natural collagen production, improve texture, enhance tone and strengthen its overall barrier function.

A3O™ COMPLEX

Calm instead of irritate. Stable in sunlight instead of breaking down. Stimulating the skin’s natural Collagen and helping set the stage for aging well*.

HYALURONIC ACID

Deeply hydrates and plumps for smoother, more elastic-feeling skin*.

SQUALANE

Helps to strengthen the skin’s natural moisture barrier to lock in hydration*.

VITAMIN E

Provides antioxidant protection and helps retain skin moisture*.

BLUE TANSY

Soothes dry, irritated skin and is gentle for sensitive skin*.

inner dose™

daily skin supplement

Designed with a strategic blend of antioxidants, adaptogens, and micronutrients, the dermatologist-formulated capsule addresses internal triggers of aging to preserve skin clarity, strength, and resilience over time*.

POLYPODIUM LEUCOTOMOS

280 mg

Helps to enhance the skin’s natural internal UV defense and photoprotection—ideal for individuals with daily sun exposure*.

ORGANIC TURMERIC

500 mg

Rebalances the body’s natural inflammatory response to help promote a calmer, more even-toned complexion*.

VITAMIN D3

2500 IU

Supports skin barrier integrity and improves overall skin vitality*.

ASTAXANTHIN

6 mg

Provides potent antioxidant protection to help preserve skin elasticity, maintain hydration, and reduce the visible signs of aging*.

HOLY BASIL / TULSI

250 mg

A powerful adaptogen known to help counter the visible effects of stress on the skin*.

A3O™ ELEMENTAL SERUM FULL INGREDIENT LIST WATER (EAU), GLYCERIN, PROPANEDIOL, BUTYROSPERMUM PARKII (SHEA) BUTTER, CAPRYLIC/CAPRIC TRIGLYCERIDE, ETHYL LINOLEATE, ACETYL ZINGERONE, ETHYLHEXYL OLIVATE, LYSOLECITHIN, SCLEROTIUM GUM, PARFUM, CAPRYLYL GLYCOL, PENTYLENE GLYCOL, TOCOPHERYL ACETATE, BAKUCHIOL, PULLULAN, XANTHAN GUM, ETHYL OLEATE, SYNTHETIC FLUORPHLOGOPITE, ETHYL PALMITATE, PHENETHYL ALCOHOL, CAPRYLHYDROXAMIC ACID, SILICA, SQUALANE, ETHYL LINOLENATE, BENZYL ALCOHOL, SODIUM HYALURONATE, TIN OXIDE, PHENOXYETHANOL, CITRIC ACID, TANACETUM ANNUUM FLOWER OIL, LIMONENE, LINALOOL, PINENE, LINALYL ACETATE, ALPHA-ISOMETHYL IONONE, BETA-CARYOPHYLLENE, ALGIN, ETHYLHEXYLGLYCERIN, TITANIUM DIOXIDE (CI 77891), IRON OXIDES (CI 77492, CI 77491).

A3O™ ELEMENTAL NIGHT CREAM FULL INGREDIENT LIST FULL INGREDIENT LIST

WATER, CAPRYLIC/CAPRIC TRIGLYCERIDE, GLYCERIN, PENTAERYTHRITYL TETRAETHYLHEXANOATE, EUPHORBIA CERIFERA (CANDELILLA) WAX, ANNONA CHERIMOLA FRUIT EXTRACT, JOJOBA ESTERS, ISOAMYL LAURATE, DIMETHICONE, HYDROGENATED ETHYLHEXYL OLIVATE, ETHYL LINOLEATE, BUTYROSPERMUM PARKII (SHEA) BUTTER, CETEARYL ALCOHOL, HELIANTHUS ANNUUS SEED WAX, CETYL ALCOHOL, ACACIA DECURRENS FLOWER WAX, BAKUCHIOL, CARNOSINE, CITRIC ACID, ECTOIN, ETHYL LINOLENATE, ETHYL OLEATE, ETHYL PALMITATE, GLYCERYL STEARATE, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, HYDROGENATED LECITHIN, PHENOXYETHANOL, PHENYLPROPANOL, PHYTOSTEROLS, POLYGLYCERIN-3, POTASSIUM SORBATE, RICINUS COMMUNIS (CASTOR) SEED OIL, SODIUM ACRYLOYLDIMETHYL TAURATE/VP CROSSPOLYMER, SODIUM BENZOATE, SODIUM CITRATE, SODIUM DEHYDROACETATE, SODIUM PHYTATE, SODIUM STEAROYL GLUTAMATE, TOCOPHEROL, TOCOPHERYL ACETATE, TRIFAROTENYL CAPRYLATE, TRIISOSTEARYL CITRATE, XANTHAN GUM.

A3O™ ELEMENTAL SERUM REFERENCES

1. Chaudhuri, R.K., Meyer, T., Premi, S. and Brash, D. (2020), Acetyl zingerone: An efficacious multifunctional ingredient for continued protection against ongoing DNA damage in melanocytes after sun exposure ends. Int J Cosmet Sci, 42: 36-45. https://doi.org/10.1111/ics.12582

2. Dhaliwal S, Rybak I, Pourang A, et al. Randomized double-blind vehicle controlled study of the effects of topical acetyl zingerone on photoaging. J Cosmet Dermatol. 2021; 20: 166–173. https://doi.org/10.1111/jocd.13464

3. Meyer, T.A.; Swindell, W.R.; Chaudhuri, R.K. Acetyl Zingerone: A Photostable Multifunctional Skincare Ingredient That Combats Features of Intrinsic and Extrinsic Skin Aging. Antioxidants 2023, 12, 1168. https://doi.org/10.3390/antiox12061168

4. Srivastava, J.; Young, M.M.; Yadav, V.K.; Phadatare, P.R.; Meyer, T.A.; Chaudhuri, R.K.; Premi, S. The Role of Acetyl Zingerone and Its Derivatives in Inhibiting UV-Induced, Incident, and Delayed Cyclobutane Pyrimidine Dimers. Antioxidants 2023, 12, 278. https://doi.org/10.3390/antiox12020278

INNER DOSE™ DAILY SKIN SUPPLEMENT REFERENCES

1. Segars K, McCarver V, Miller RA. Dermatologic Applications of Polypodium leucotomos: A Literature Review. J Clin Aesthet Dermatol. 2021 Feb;14(2):50-60. Epub 2021 Feb 1. PMID: 34221229; PMCID: PMC8211346.

2. Zundell MP, Katz A, Shah M, Burshtein J, Rigel D, Zakria D. The Utility of Oral Polypodium Leucotomos Extract for Dermatologic Diseases: A Systematic Review. J Drugs Dermatol. 2025 Apr 1;24(4):346-351. doi: 10.36849/JDD.8410. PMID: 40196953.

3. Vaughn AR, Branum A, Sivamani RK. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytother Res. 2016 Aug;30(8):1243-64. doi: 10.1002/ptr.5640. Epub 2016 May 23. PMID: 27213821.

4. Mata IRD, Mata SRD, Menezes RCR, Faccioli LS, Bandeira KK, Bosco SMD. Benefits of turmeric supplementation for skin health in chronic diseases: a systematic review. Crit Rev Food Sci Nutr. 2021;61(20):3421-3435. doi: 10.1080/10408398.2020.1798353. Epub 2020 Jul 27. PMID: 32713186.

5. Chang SW, Lee HC. Vitamin D and health - The missing vitamin in humans. Pediatr Neonatol. 2019 Jun;60(3):237-244. doi: 10.1016/j.pedneo.2019.04.007. Epub 2019 Apr 17. PMID: 31101452.

6. Davinelli S, Nielsen ME, Scapagnini G. Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review. Nutrients. 2018 Apr 22;10(4):522. doi: 10.3390/nu10040522. PMID: 29690549; PMCID: PMC5946307.

7. Ng QX, De Deyn MLZQ, Loke W, Foo NX, Chan HW, Yeo WS. Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies. J Diet Suppl. 2021;18(2):169-182. doi: 10.1080/19390211.2020.1739187. Epub 2020 Mar 23. PMID: 32202443.

8. Lima SGM, Freire MCLC, Oliveira VDS, Solisio C, Converti A, de Lima ÁAN. Astaxanthin Delivery Systems for Skin Application: A Review. Mar Drugs. 2021 Sep 9;19(9):511. doi: 10.3390/md19090511. PMID: 34564173; PMCID: PMC8471810.

9. Hilt B, Langård S, Lund-Larsen PG, Lien JT. Previous asbestos exposure and smoking habits in the county of Telemark, Norway--a cross-sectional population study. Scand J Work Environ Health. 1986 Dec;12(6):561-6. doi: 10.5271/sjweh.2106. PMID: 3493526.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

MEET THE ELEMENTAL SERUM

Powered by our patent-pending A30™ complex

A3O™ is a next-generation antioxidant engineered to target the visible signs of cellular aging — without the irritation or instability of Vitamin C.

Meet A3O™

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Lindsay T

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8 hours ago

This serum is amazing! My skin glows for aong long after I use this. This has brought so much life back to my skin.

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Lindsay T

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8 hours ago

This night cream is amazing! My skin is soft and hydrated. I highly reccomend!

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Teresa W

Verified buyer

Age:65-74

Benefits:Improved Hydration, Improved Skin Texture

Skin concerns:Aging skin

Skin type:Aging

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yesterday

Love it!

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Jacqueline N

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Age:55-64

Benefits:Softened Fine Lines, Brightened Complexion, Improved Skin Texture, Smoothed Crow's Feet

Skin concerns:Redness, Aging skin, Fine lines / wrinkles

Skin type:Combination, Sensitive, Aging

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yesterday

Amazing

In my younger years I was skincare certified I have tried all the best of the best this product by far is the most effective within 2 days I saw a difference in skin under my eyes all over. The scent is delicious the texture is simply perfect I subscribed to it after a weeks use. Thank you Martha for creating such an amazing product !

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Kathleene E

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Age:65-74

Skin concerns:Aging skin, Redness, Dullness, Dryness

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2 days ago

Liquid Gold

I have been using the serum and night cream for about three weeks. Can I just say that these products are liquid gold?! After applying the serum, my face feels tighter and smoother. I apply the night cream sparingly as it is very rich. Together these products have made my 66 yr. old face look smoother. I will re-order and continue to use, I've tried so many serums and creams but these products del... Read more

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INTERNAL SUPPORT. EXTERNAL DEFENSE.

Our A3O™ Complete Skin Renewal bundle forms a streamlined, clinically-advanced system designed to restore skin clarity, strengthen the barrier, and build long-term resilience—from the inside out.

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Discover the A3O™ Complete Skin Renewal

FAQ

WE’VE DONE OUR RESEARCH

Can I use this bundle with other skincare or supplements?

PlusMinus

Yes, the serum and night cream can be incorporated into your routine with most skincare products. Avoid using potent exfoliating acids (AHAs/BHAs) on the same evening as the retinoid night cream to minimize irritation. The supplement can be combined with other general wellness products but consult your healthcare provider if taking additional targeted supplements.

Who is this bundle suitable for?

PlusMinus

This bundle is ideal for all skin types, including sensitive skin, and supports skin showing early signs of aging, uneven tone, dehydration, or stress-related changes.

how often should i use the serum?

PlusMinus

Apply morning and night to clean, dry skin. A3O™ is gentle enough for daily use — even for sensitive skin.

When should I take Inner Dose™ Daily Skin Supplement ?

PlusMinus

For optimal absorption, we recommend taking Inner Dose™ Daily Skin Supplement ™ in the morning with food. However it’s safe to take at any time that works for your routine.

Will this work for sensitive skin?

PlusMinus

Yes. A3O™ was designed to be a smarter, more stable alternative to Vitamin C — with none of the irritation, stinging, or sensitivity many people experience with traditional actives. It’s tested safe for sensitive skin and post-procedure use.

WHAT PAIRS WELL WITH THE SERUM?

PlusMinus

For optimal results, pair with our Inner Dose™ Daily Skin Supplement to target aging from the inside out. You can also layer with your favorite moisturizer or SPF.

Can I use this bundle during pregnancy or breastfeeding?

PlusMinus

The A3O™ Elemental Night Cream contains a targeted retinoid and should be avoided during pregnancy or breastfeeding unless approved by your healthcare provider. The Elemental Serum and Inner Dose™ Daily Skin Supplement are generally considered safe, but it is recommended to consult your doctor before use.

How long will it take to see results?

PlusMinus

With Inner Dose™ Daily Skin Supplement, improvements in clarity and tone can appear in 2–4 weeks, with continued benefits over 8–12 weeks.

With A3O™ Elemental Serum and A3O™ Elemental Night Cream, expect visible results for brighter and smoother skin within 4-6 weeks. For best results use 8-12 weeks to help improve tone, clarity, and fine lines.

Consistent use helps maximize results.

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