Skin Longevity System 2-Pack – Elm Biosciences

NEW

01/07

4.8 (429)

Skin Longevity System 2-Pack

~~Regular Price:$430.00~~Sale Price:$309.60

Stabilizes Skin

Refines Texture

An advanced two-step approach engineered to strengthen the skin, support renewal, and safeguard long-term function.

A proactive ritual designed to safeguard the skin’s long-term health. A3O™ Night Cream delivers a targeted retinoid to support ongoing surface renewal, improving texture, clarity, and radiance with consistent use. Inner Dose™ Daily Skin Supplement addresses internal triggers of aging—including inflammation, oxidative stress, and hormonal imbalance—helping maintain a healthy baseline for skin recovery. Together, this duo helps future-proof the complexion, promoting durable, resilient, and luminous skin over time.

2x A3O™ Elemental Night Cream: e50 mL / 1.69 fl oz

2x Inner Dose™ Daily Skin Supplement: 60 capsules / 2-month supply

1 Month

2 Month

SubscriptionSAVE $120.40~~$430.00~~ $309.60

Delivery every 60 Days
One supplement jar to start; refills in pouches
Skip or cancel anytime
Complimentary shipping

One-time purchase~~$430.00~~ $387.00

Add to Cart

HSA/FSA eligible Save an average of 30%

Learn more

Skin Longevity System 2-Pack

Add to Cart

An advanced two-step approach engineered to strengthen the skin, support renewal, and safeguard long-term function.

2x A3O™ Elemental Night Cream: e50 mL / 1.69 fl oz

2x Inner Dose™ Daily Skin Supplement: 60 capsules / 2-month supply

Ingredients

Trifarotenyl Caprylate – A selective, retinoid derivative that helps improve the appearance of skin texture while being suitable for sensitive skin.
A3O™ Complex – Our patent-pending anti-senescence A3O™ Complex that delivers smoothing, brightening, and firming benefits rival those of Vitamin C, with superior tolerability and no irritation.
Ectoin – An antioxidant that helps protect skin from environmental stressors while supporting the skin’s moisture barrier and soothes dry, irritated skin.
Carnosine – A potent peptide that helps protect the skin from the visible signs of aging, supports firmer feeling skin, and brightens dull-looking skin.

Recommended usage

Apply a pea-sized amount to clean, dry skin nightly, gradually increasing frequency if new to retinoids. Avoid the immediate eye area. Always follow with daytime sunscreen.

Benefits

Smooths the look of fine lines and skin texture
Supports firm and elastic skin
Provides overnight hydration and skin barrier support
Promotes brighter, more even-looking skin
Designed to be gentle enough for nightly use

Complete the routine

A3O™ Complete Skin Renewal

~~Regular price: $350.00~~Sale price: $315.00

Add to Cart
Learn More

[View product - A3O™ Complete Skin Renewal - Default Title](/content/products/a3o-complete-skin-renewal?variant=46078711529625 "View product - A3O™ Complete Skin Renewal - Default Title"/index.html)

How to Use

Engineered to Support Skin Longevity and Regeneration

Take [Inner Dose™ Daily Skin Supplement](/content/products/inner-dose-daily-skin-supplement-starter-kit "Inner Dose™ Daily Skin Supplement Starter Kit"/index.html) capsules daily with food,  preferably in the morning.
On clean skin, apply a pea-sized amount of [A3O™ Elemental Night Cream](/content/products/a3o-elemental-night-cream "A3O™ Elemental Night Cream"/index.html) to dry skin, avoiding the eye area.
Massage gently for even coverage.
For best results, pair with daily sunscreen and consistent nightly use.

meet a3o™

It's Time to Rethink Your Vitamin C

Our patent-pending anti-senescence A3O™ Complex delivers smoothing, brightening, and firming benefits rival those of Vitamin C, with superior tolerability and no irritation.

A3O™

VITAMIN C

Hydration

Firmness

Wrinkles

Elasticity

Redness

Safe for Daily Use

Advanced Ingredients, Intelligently Sourced

Our ingredients are meticulously selected to create formulas that bring breakthrough science into effective daily skincare.

Full List

Our proprietary complex that protects and supports

A3O™ Complex

Improves texture and clarity

TRIFAROTENYL CAPRYLATE

Supports skin barrier

Ectoin

Improves firmness

Carnosine

Supports photoprotection

Polypodium Leucotomos

Calms and soothes

Organic Turmeric

Adds vitality

Vitamin D3

Maintains skin elasticity

Astaxanthin

Adapts and balances

Holy Basil / Tulsi

01/09

Full List

a3o™ elemental night cream

A transformative, next-generation retinoid with no prescription needed.

A3O™ COMPLEX

Combining Acetyl Zingerone, Bakuchiol, and a fatty acid ester, our Patent-pending, triple-pathway anti-senescent molecule helps firm skin, enhances tone, and brightens the complexion with results that rival Vitamin C, without the irritation.*

Developed over years of R&D, including clinical work and published research on individual components by our dermatologist-led medical advisory board, we were very intentional about each ingredient and the optimal method to combine them in our complex. We believe this will reset the industry’s expectations for antioxidant molecules moving forward.

Calm instead of irritate. Stable in sunlight instead of breaking down. Stimulating the skin’s natural Collagen and helping set the stage for aging well*.

TRIFAROTENYL CAPRYLATE

A selective, retinoid derivative that helps improve the appearance of skin texture while being suitable for sensitive skin*.

ECTOIN

An antioxidant that helps protect skin from environmental stressors while supporting the skin’s moisture barrier and soothes dry, irritated skin*.

CARNOSINE

A potent peptide that helps protect the skin from the visible signs of aging, supports firmer feeling skin, and brightens dull-looking skin*.

inner dose™

daily skin supplement

Designed with a strategic blend of antioxidants, adaptogens, and micronutrients, the dermatologist-formulated capsule addresses internal triggers of aging to preserve skin clarity, strength, and resilience over time*.

POLYPODIUM LEUCOTOMOS

280 mg

Helps to enhance the skin’s natural internal UV defense and photoprotection—ideal for individuals with daily sun exposure*.

ORGANIC TURMERIC

500 mg

Rebalances the body’s natural inflammatory response to help promote a calmer, more even-toned complexion*.

VITAMIN D3

2500 IU

Supports skin barrier integrity and improves overall skin vitality*.

ASTAXANTHIN

6 mg

Provides potent antioxidant protection to help preserve skin elasticity, maintain hydration, and reduce the visible signs of aging*.

HOLY BASIL / TULSI

250 mg

A powerful adaptogen known to help counter the visible effects of stress on the skin*.

A3O™ ELEMENTAL NIGHT CREAM FULL INGREDIENT LIST FULL INGREDIENT LIST

WATER, CAPRYLIC/CAPRIC TRIGLYCERIDE, GLYCERIN, PENTAERYTHRITYL TETRAETHYLHEXANOATE, EUPHORBIA CERIFERA (CANDELILLA) WAX, ANNONA CHERIMOLA FRUIT EXTRACT, JOJOBA ESTERS, ISOAMYL LAURATE, DIMETHICONE, HYDROGENATED ETHYLHEXYL OLIVATE, ETHYL LINOLEATE, BUTYROSPERMUM PARKII (SHEA) BUTTER, CETEARYL ALCOHOL, HELIANTHUS ANNUUS SEED WAX, CETYL ALCOHOL, ACACIA DECURRENS FLOWER WAX, BAKUCHIOL, CARNOSINE, CITRIC ACID, ECTOIN, ETHYL LINOLENATE, ETHYL OLEATE, ETHYL PALMITATE, GLYCERYL STEARATE, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, HYDROGENATED LECITHIN, PHENOXYETHANOL, PHENYLPROPANOL, PHYTOSTEROLS, POLYGLYCERIN-3, POTASSIUM SORBATE, RICINUS COMMUNIS (CASTOR) SEED OIL, SODIUM ACRYLOYLDIMETHYL TAURATE/VP CROSSPOLYMER, SODIUM BENZOATE, SODIUM CITRATE, SODIUM DEHYDROACETATE, SODIUM PHYTATE, SODIUM STEAROYL GLUTAMATE, TOCOPHEROL, TOCOPHERYL ACETATE, TRIFAROTENYL CAPRYLATE, TRIISOSTEARYL CITRATE, XANTHAN GUM.

REFERENCES

1. Segars K, McCarver V, Miller RA. Dermatologic Applications of Polypodium leucotomos: A Literature Review. J Clin Aesthet Dermatol. 2021 Feb;14(2):50-60. Epub 2021 Feb 1. PMID: 34221229; PMCID: PMC8211346.

2. Zundell MP, Katz A, Shah M, Burshtein J, Rigel D, Zakria D. The Utility of Oral Polypodium Leucotomos Extract for Dermatologic Diseases: A Systematic Review. J Drugs Dermatol. 2025 Apr 1;24(4):346-351. doi: 10.36849/JDD.8410. PMID: 40196953.

3. Vaughn AR, Branum A, Sivamani RK. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytother Res. 2016 Aug;30(8):1243-64. doi: 10.1002/ptr.5640. Epub 2016 May 23. PMID: 27213821.

4. Mata IRD, Mata SRD, Menezes RCR, Faccioli LS, Bandeira KK, Bosco SMD. Benefits of turmeric supplementation for skin health in chronic diseases: a systematic review. Crit Rev Food Sci Nutr. 2021;61(20):3421-3435. doi: 10.1080/10408398.2020.1798353. Epub 2020 Jul 27. PMID: 32713186.

5. Chang SW, Lee HC. Vitamin D and health - The missing vitamin in humans. Pediatr Neonatol. 2019 Jun;60(3):237-244. doi: 10.1016/j.pedneo.2019.04.007. Epub 2019 Apr 17. PMID: 31101452.

6. Davinelli S, Nielsen ME, Scapagnini G. Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review. Nutrients. 2018 Apr 22;10(4):522. doi: 10.3390/nu10040522. PMID: 29690549; PMCID: PMC5946307.

7. Ng QX, De Deyn MLZQ, Loke W, Foo NX, Chan HW, Yeo WS. Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies. J Diet Suppl. 2021;18(2):169-182. doi: 10.1080/19390211.2020.1739187. Epub 2020 Mar 23. PMID: 32202443.

8. Lima SGM, Freire MCLC, Oliveira VDS, Solisio C, Converti A, de Lima ÁAN. Astaxanthin Delivery Systems for Skin Application: A Review. Mar Drugs. 2021 Sep 9;19(9):511. doi: 10.3390/md19090511. PMID: 34564173; PMCID: PMC8471810.

9. Hilt B, Langård S, Lund-Larsen PG, Lien JT. Previous asbestos exposure and smoking habits in the county of Telemark, Norway--a cross-sectional population study. Scand J Work Environ Health. 1986 Dec;12(6):561-6. doi: 10.5271/sjweh.2106. PMID: 3493526.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Customer reviews

4.75

Outline star

Filled star

429 reviews

Write a review

Filter

LatestOldestHighest ratedLowest ratedMost helpful

Sort by: Highest rated

All18-2425-3435-4445-5455-6465-7475+

Age

AllAging skinAcne / breakoutsRednessDullnessDrynessFine lines / wrinkles

Skin concerns

All1 star2 stars3 stars4 stars5 stars

Rating

Photos & videos

Lindsay T

Verified buyer

Outline star

Filled star

8 hours ago

This night cream is amazing! My skin is soft and hydrated. I highly reccomend!

Review for A3O™ Elemental Night Cream

Helpful

Up vote review action - {votes}

Down vote review action - {votes}

Suzanne H

Verified buyer

Age:55-64

Skin concerns:Dryness, Dullness, Aging skin, Fine lines / wrinkles

Outline star

Filled star

last month

Amazing product!!!

Review for A3O™ Elemental Night Cream

Would recommend

Helpful

Up vote review action - {votes}

Down vote review action - {votes}

Marqueritha C

Verified buyer

Outline star

Filled star

last month

Great product. Highly recommend.

Review for A3O™ Elemental Night Cream

Helpful

Up vote review action - {votes}

Down vote review action - {votes}

Christine V

Verified buyer

Outline star

Filled star

last month

The tumeric is hard on my stomach so i am splitting up the capsules into breakfast and last meal of the day.

Review for Inner Dose™ Daily Skin Supplement Refill Only

Helpful

Up vote review action - {votes}

Down vote review action - {votes}

Robyn F

Verified buyer

Outline star

Filled star

2 months ago

I have used this itemfor about 3 months. It works well but a little on the pricey sofe

Review for A3O™ Elemental Night Cream

Helpful

Up vote review action - {votes}

Down vote review action - {votes}

See more reviews

Reviewed on See Elm Biosciences on Junip (opens in a new tab)

MEET THE ELEMENTAL SERUM

Powered by our patent-pending A30™ complex

A3O™ is a next-generation antioxidant engineered to target the visible signs of cellular aging — without the irritation or instability of Vitamin C.

Meet A3O™

INTERNAL SUPPORT. EXTERNAL DEFENSE.

Our A3O™ Complete Skin Renewal bundle forms a streamlined, clinically-advanced system designed to restore skin clarity, strengthen the barrier, and build long-term resilience—from the inside out.

Start Your Protocol

Discover the A3O™ Complete Skin Renewal

FAQ

WE’VE DONE OUR RESEARCH

Can I use this alongside other actives like AHAs or BHAs?

PlusMinus

Yes, but we recommend using them on different nights. Layering acids with A3O™ Elemental Night Cream can irritate the skin.

When will I see results?

PlusMinus

With Inner Dose™ Daily Skin Supplement, improvements in clarity and tone can appear in 2–4 weeks, with continued benefits over 8–12 weeks.

With A3O™ Elemental Night Cream, expect visible results for brighter and smoother skin within 4-6 weeks. For best results use 8-12 weeks to help improve tone, clarity, and fine lines.

Consistent use helps maximize results.

Can I use A3O™ Elemental Night Cream during the day?

PlusMinus

We recommend only using A3O™ Elemental Night Cream in the evening, as retinoids can make your skin more sensitive to sunlight. Always apply sunscreen during the day.

Who is A3O™ Elemental Night Cream ideal for?

PlusMinus

This formula is suitable for most skin types and was developed specifically with sensitive skin in mind. It’s ideal for those looking to improve texture, tone, early signs of aging, or congestion with a gentle, targeted retinoid.

WHO ARE YOUR PRODUCTS FORMULATED FOR?

PlusMinus

Elm is designed for real skin — including sensitive, aging, hormonal, or inflammation-prone. Our formulas are clinically tested to work across a wide range of tones, textures, and needs.

Can I use this while pregnant or breastfeeding?

PlusMinus

Retinoids should be avoided during pregnancy or breastfeeding unless specifically approved by your healthcare provider.

Is this compatible with other supplements?

PlusMinus

Yes. Inner Dose™ was formulated to complement — not compete with — most daily vitamins and wellness regimens. If you’re on medication or have a health condition, we recommend checking with your physician.

Will this work for sensitive skin?

PlusMinus

Yes. A3O™ was designed to be a smarter, more stable alternative to Vitamin C — with none of the irritation, stinging, or sensitivity many people experience with traditional actives. It’s tested safe for sensitive skin and post-procedure use.

View All FAQs