A3O™ Elemental Night Cream – Elm Biosciences

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01/08

302 Reviews

A3O™ Elemental Night Cream

Regular Price:$165.00Sale Price:$132.00

Firms Skin

Hydrates

Supports Elasticity

A transformative, next-generation retinoid—no prescription needed.

A restorative treatment designed to help your skin appear renewed overnight. This advanced formula pairs a modern, targeted retinoid with our A3O™ Proprietary Complex, Ectoin, and lipids to smooth the appearance of fine lines, help the skin feel firm, and deeply hydrate your skin while you sleep.

Ideal for anyone who wants visible results from a retinoid without irritation, gentle enough for nightly use.

e50 mL / 1.69 fl oz

Subscription purchase typeMONTHLY DELIVERYSave $33.00Regular price: $165.00 $132.00

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One time only purchase typeONE-TIME PURCHASE$165.00

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For best results, pair with:

A3O™ Elemental SerumGET BOTH & SAVE –$216 $300

A transformative, next-generation retinoid—no prescription needed.

Ideal for anyone who wants visible results from a retinoid without irritation, gentle enough for nightly use.

e50 mL / 1.69 fl oz

Ingredients

Recommended usage

Apply a pea-sized amount to clean, dry skin nightly, gradually increasing frequency if new to retinoids. Avoid the immediate eye area. Always follow with daytime sunscreen.

Retinoids should be avoided during pregnancy or breastfeeding unless specifically approved by your healthcare provider.

Benefits

how to use

SLEEP TIGHT. WAKE BRIGHT.

  1. Apply a pea-sized amount to clean, dry skin as the final step in your night-time routine.

  2. Gently massage over the face, neck, décolleté, and hands, avoiding the immediate eye area.

  3. For best results, use nightly. If you are new to retinoids, 
start with every other night for the first week, then increase as tolerated.

  4. Always use sunscreen during the day when using retinoid-based treatments.

  5. This product should be avoided during pregnancy or breastfeeding unless approved by your healthcare provider.

meet a3o™

meet a3o™

It's Time to Rethink Your Vitamin C

Our patent-pending anti-senescence A3O™ Complex delivers smoothing, brightening, and firming benefits rival those of Vitamin C, with superior tolerability and no irritation.

A3O™

A3O™

VITAMIN C

Hydration

Firmness

Wrinkles

Elasticity

Redness

Safe for Daily Use

A3O™ ELEMENTAL NIGHT CREAM

The A3O™ Elemental Night Cream Experience

A velvety, medium-weight cream with a soft, satin finish

Cushiony, smoothing, and deeply moisturizing without heaviness

Subtle and clean with no added fragrance

Dryness, dullness, uneven texture, early signs of aging, and sensitive skin

Cruelty-Free. Vegan. 
Gluten-Free.
Dermatologist-Tested & Developed.

Advanced Ingredients, Intelligently Sourced

Our ingredients are meticulously selected to create formulas that bring breakthrough science into effective daily skincare.

Full List

Our proprietary complex that protects and supports

01

A3O™ Complex

Improves texture and clarity

02

TRIFAROTENYL CAPRYLATE

Supports skin barrier

03

Ectoin

Improves firmness

04

Carnosine

01/04

Full List

a3o™ elemental night cream

A transformative, next-generation retinoid with no prescription needed.

A3O™ COMPLEX

Combining Acetyl Zingerone, Bakuchiol, and a fatty acid ester, our ​​Patent-pending, triple-pathway anti-senescent molecule helps firm skin, enhances tone, and brightens the complexion with results that rival Vitamin C, without the irritation.*

Developed over years of R&D, including clinical work and published research on individual components by our dermatologist-led medical advisory board, we were very intentional about each ingredient and the optimal method to combine them in our complex. We believe this will reset the industry’s expectations for antioxidant molecules moving forward.

Calm instead of irritate. Stable in sunlight instead of breaking down. Stimulating the skin’s natural Collagen and helping set the stage for aging well*.

TRIFAROTENYL CAPRYLATE

​​​​A selective, retinoid derivative that helps improve the appearance of skin texture while being suitable for sensitive skin*.​​​​

ECTOIN

​​​​An antioxidant that helps protect skin from environmental stressors while supporting the skin’s moisture barrier and soothes dry, irritated skin*.​​

CARNOSINE

​​​​A potent peptide that helps protect the skin from the visible signs of aging, supports firmer feeling skin, and brightens dull-looking skin*.​

FULL INGREDIENT LIST WATER, CAPRYLIC/CAPRIC TRIGLYCERIDE, GLYCERIN, PENTAERYTHRITYL TETRAETHYLHEXANOATE, EUPHORBIA CERIFERA (CANDELILLA) WAX, ANNONA CHERIMOLA FRUIT EXTRACT, JOJOBA ESTERS, ISOAMYL LAURATE, DIMETHICONE, HYDROGENATED ETHYLHEXYL OLIVATE, ETHYL LINOLEATE, BUTYROSPERMUM PARKII (SHEA) BUTTER, CETEARYL ALCOHOL, HELIANTHUS ANNUUS SEED WAX, CETYL ALCOHOL, ACACIA DECURRENS FLOWER WAX, BAKUCHIOL, CARNOSINE, CITRIC ACID, ECTOIN, ETHYL LINOLENATE, ETHYL OLEATE, ETHYL PALMITATE, GLYCERYL STEARATE, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, HYDROGENATED LECITHIN, PHENOXYETHANOL, PHENYLPROPANOL, PHYTOSTEROLS, POLYGLYCERIN-3, POTASSIUM SORBATE, RICINUS COMMUNIS (CASTOR) SEED OIL, SODIUM ACRYLOYLDIMETHYL TAURATE/VP CROSSPOLYMER, SODIUM BENZOATE, SODIUM CITRATE, SODIUM DEHYDROACETATE, SODIUM PHYTATE, SODIUM STEAROYL GLUTAMATE, TOCOPHEROL, TOCOPHERYL ACETATE, TRIFAROTENYL CAPRYLATE, TRIISOSTEARYL CITRATE, XANTHAN GUM.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

MEET THE ELEMENTAL SERUM

Powered by our patent-pending A30™ complex

A3O™ is a next-generation antioxidant engineered to target the visible signs of cellular aging — without the irritation or instability of Vitamin C.

Meet A3O™

Customer reviews

4.71

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302 reviews

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LT

Lindsay T

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8 hours ago

This night cream is amazing! My skin is soft and hydrated. I highly reccomend!

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Suzanne H

Verified buyer

Age:55-64

Skin concerns:Dryness, Dullness, Aging skin, Fine lines / wrinkles

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last month

Amazing product!!!

Amazing product!!!

Would recommend

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Marqueritha C

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last month

Great product. Highly recommend.

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Robyn F

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2 months ago

I have used this itemfor about 3 months. It works well but a little on the pricey sofe

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Joan C

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3 months ago

So moisturizing

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Reviewed on See Elm Biosciences on Junip (opens in a new tab)

INTERNAL SUPPORT. EXTERNAL DEFENSE.

Our A3O™ Complete Skin Renewal bundle forms a streamlined, clinically-advanced system designed to restore skin clarity, strengthen the barrier, and build long-term resilience—from the inside out.

Start Your Protocol

Discover the A3O™ Complete Skin Renewal

FAQ

WE’VE DONE OUR RESEARCH

Can I use this alongside other actives like AHAs or BHAs?

PlusMinus

Yes, but we recommend using them on different nights. Layering acids with A3O™ Elemental Night Cream can irritate the skin.

When will I see results?

PlusMinus

Visible results for brighter and smoother skin can be seen within 4-6 weeks. For best results, use 8-12 weeks to help improve tone, clarity, and fine lines.

Can I use A3O™ Elemental Night Cream during the day?

PlusMinus

We recommend only using A3O™ Elemental Night Cream in the evening, as retinoids can make your skin more sensitive to sunlight. Always apply sunscreen during the day.

Can I use this while pregnant or breastfeeding?

PlusMinus

Retinoids should be avoided during pregnancy or breastfeeding unless specifically approved by your healthcare provider.

Who is A3O™ Elemental Night Cream ideal for?

PlusMinus

This formula is suitable for most skin types and was developed specifically with sensitive skin in mind. It’s ideal for those looking to improve texture, tone, early signs of aging, or congestion with a gentle, targeted retinoid.

View All FAQs

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